Should I quit?
2024.11.25 12:50 Rolly2k15 Should I quit?
Hey guys I’ve been working 9-6am M-F since July and I really think I’m starting to lose it. My sleep is so irregular, I can’t stay asleep for more than 3 hours at a time, I feel weaker than before I started. I’m more irritated.
I need the money, we all do, but I was planning to work this until at least February. Do you guys have any advice or anything? The work is alright and the pay is good but I really feel like I’m losing “me” that I was before.
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2024.11.25 12:50 reaperssoo Xbox: W: Just any somber weapons or runes someone wants to lay down H: Karma
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2024.11.25 12:50 Noledgebase Mastering Java + Spring Boot: REST APIs and Microservices ($19.99 to FREE)
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2024.11.25 12:50 Possible-Falcon2052 Send me your best asshole pic and I HAVE to stroke to it, no matter what ;) 05f24709ae5755b0bf349273b0772eea962f23501a5d7ab9c9066fcbb77d10d907
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2024.11.25 12:50 jojo199696 Looking to make friends in Peshawar
28m from Karachi
So I have recently come to peshawar and Im bicurious. I wanna hookup with M or F either. But whats up with the lack of avenues to meet people here?
Any guy or girl looking for that, need to make friends and have fun.
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2024.11.25 12:50 Noledgebase YouTube Marketing: Become a Digital TV Star in Your Niche ($39.99 to FREE)
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2024.11.25 12:50 Traditional-Care-87 [Hypothesis] Nutritional requirements for maintaining SSRI (SNRI）
I have a bizarre (silly?) hypothesis about SSRIs and SNRIs, and I'd like to hear your opinions on it.
I was using Cymbalta, but the effect disappeared after two months, and even increasing the dose no longer worked at all. (It had worked perfectly until then.)
This is called the poop out phenomenon, and someone on reddit told me that it is also related to receptor downregulation.
I accepted that, and while searching for other ways, I came across Piracetam.
When I took Piracetam, my brain fog and fatigue were significantly reduced. However, I heard that Piracetam sometimes requires choline, and that if you do not take that nutrient, the effect will disappear or a headache will occur.
Here, I felt that Cymbalta and Piracetam might have a similar mechanism.
In other words, just as Piracetam requires choline (some people need it), the hypothesis came to me that Cymbalta also requires some kind of nutrition to maintain its effect, and if you neglect to take it, it will no longer work.
Of course, the mechanism by which antidepressants stop working may be different for each person, and I do not claim that my hypothesis completely explains everything.
However, to simplify things, I thought that for example, in the case of Cymbalta, the effect may be maintained if you take something that is a source of nutrition for serotonin and norepinephrine.
The questions I would like to ask here are:
① Like the relationship between piracetam and choline, how likely is it that a deficiency of a specific nutrient is involved in the weakening of the effectiveness of Cymbalta (or SSRIs and SNRIs in general)?
② Based on my hypothesis, what nutrients do you think are important for making Cymbalta work again?
③ I thought about taking B vitamins and magnesium for serotonin, and copper and vitamin C for norepinephrine, but is this a hasty idea?
④ This may be off topic, but I have a strange reaction to vitamins. For example, when I take vitamin B (especially vitamin B12), I get auditory hallucinations and feel fatigued. Is there something wrong with methylation? In this case, should I selectively take only the B vitamins involved in serotonin synthesis?
⑤My main symptoms are brain fog, ADHD, chronic fatigue, dry throat, and dry eyes. Why do psychiatric drugs solve these? Cymbalta improved these "physical and physical" symptoms all at once in the first two months. I have almost no psychiatric symptoms at all.
This is a long story, so a partial answer is fine. My life was a mess because of chronic fatigue and brain fog, and I really felt like I got my life back during the period when Cymbalta was effective (not manic), so I hope Cymbalta will work again. Is there any good way? I'm ignorant, so please feel free to point out any points that may be useful, even if they are unrelated to my hypothesis.
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2024.11.25 12:50 ART__007 Maadi work space
حد ممكن يريكومند ورك سبيس كويس في المعادي ؟ واسعاره حلوه
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2024.11.25 12:50 Jassanti Failed Delivery Attempts and Reasons
Gaano po kayo kadalas maka-experience ng failed delivery attempt? Either sa receiver or courier side po. Ano po reason/s? Baka rin po meron articles/posts about sa failed delivery attempts ng shopee or lazada, pacomment na lang po. For research lang po. TYIA!
View Poll
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2024.11.25 12:50 Automatic-Strike-100 Anghkoey
I’m confused how Jade and Tabitha understood “anghkoey” to be remember. Maybe I missed something?
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2024.11.25 12:50 JaredOLeary I created the ultimate samurai
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2024.11.25 12:50 Dreamlight_Belle Can I play both on PC and Switch?
Hi😃 I was wondering... Can I play Dreamlight Valley both on PC and Switch or does it mess up? Anyone who plays on both devices can help me? Thank you 🫶🏻
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2024.11.25 12:50 Noledgebase Media Training Public Speaking Training for Candidates ($54.99 to FREE)
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2024.11.25 12:50 r_mansoori How to make sub directories on WordPress
i have a blog and i want to cover all the questions in my niche that don't require a big article. So I decided to make a sub directory of name example com/hub so how can I do it, also I want to include it in my root domain sitemap. i didn't found video or article, please guys help me. for example backlink do it
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2024.11.25 12:50 GGC64 Shortcut or All Systems Go - (2) OG 5⭐️ or 25 stars
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2024.11.25 12:50 cpc5000 Two non performance related hot takes.
1) The Texans should wear the H-Town "H" uniforms whenever we play the Titans at home.
2) I don't understand NRG tailgating. They just make bad NRG parking even worse. Why not just do it at home?
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2024.11.25 12:50 huflit1997 "Birthplace: Unknown" She is not human, isnt she ?
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2024.11.25 12:50 Noledgebase Site Engineer Mastery in Steel and Civil PEB Construction ($44.99 to FREE)
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2024.11.25 12:50 may-j-u Neurodivergent FMC
Does anyone know any good RH with a neurodivergent FMC? She could have anything from ADHD to autism, I'm just looking for representation.
RH with an FMC with physical disability (deaf, blind, mute, wheelchair-bound, etc.) would be good too!
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2024.11.25 12:50 flecksable_flyer [CHAT] ISO a cross-stitch magazine to buy.
I don't know the name of the magazine but the year is the early 2000s. On the front cover is a picture of a black and white cat w/poinsettia stocking. I'm looking for this stocking. Any help would be appreciated.
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2024.11.25 12:50 Noledgebase Sales Skills Training: Explode Your Sales with Online Video ($49.99 to FREE)
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2024.11.25 12:50 Spec_XD Got my first ever (working) drawing tablet! :D
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2024.11.25 12:50 divjnky Sprinkler Blowouts?
If you have a sprinkler system here in Knoxville do you get it blown out/winterized yearly or just let it ride? If you have it blown out who do you use?
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2024.11.25 12:50 Zestyclose-Hope8550 Qui dispo pour discuter sur Julia ensemble ?
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2024.11.25 12:50 esreverflash Constant hypnic jerks ruining sleep
I started experiencing them in June 2024, especially after playing sports like basketball. I stopped exercising all together for around 2-3 months and took Magnesium, Potassium, Vitamin C and D, and Iron supplements everyday. I even started running again a few weeks back around 2-3 miles per day and was still able to sleep fine. Recently since I started playing basketball again, I've started to experience them again, and regardless of how top up on electrolytes I am, I doesn't seem to make a difference. For years I used to play sports consistently and then fall asleep so easily because of how physically exhausted I was, but now the jerks seem to stop that from happening. Just last night I was laying in bed at 9:30 and didn't fall asleep till almost 12 because I would twitch or jerk anytime I was about to fall asleep. Any advice is appreciated!
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