2024.11.25 23:50 speedymed Genome sequencing/targeted therapy
Hi all! I was directed over here after posting on cancer. I was diagnosed with undifferentiated pleomorphic sarcoma of my iliac bone a few weeks ago. Just got my port placed and will be started MAP therapy after (hopefully) fertility preservation. I was offered whole genome sequencing as part of a research study at my treating facility. When speaking with the researcher, she mentioned the possibility of targeted therapy depending on the mutations identified. I myself am a resident physician and have done extensive research on osteosarcoma treatments. From my understanding, targeted therapy for osteosarcoma is in its infancy at best and at worst, has proven not to work. To preface, either way I will be participating in the study. If it doesn’t provide better outcomes for my case, hopefully it contributes to future advances for others diagnosed with this terrible disease.
My question is, has anyone had full genome sequencing for osteosarcoma or bone sarcoma and had targeted therapy (in additional to the traditional chem and surgery) based on the mutations identified?
submitted by speedymed to sarcoma [link] [comments]
2024.11.25 23:50 SnakeDoctor00 XFX or Gigabyte 7800XT, or other recommendations.
I bought a 7600XT for $225 for my new build and while I think it was a good deal I think I’m going to instead use that to replace the RX580 in my current PC that’s being passed down to my son.
I don’t do much gaming but when I do it’s GTA V and now Black Ops 6. I don’t have any desire for the latest and greatest and I can barely tell the differences when I see various images of game detail that some GPU add. I just want to casually play at decent settings on 1440p.
I’m looking at the 7800XT from either XFX in the Speedster Merc319 or the Gigabyte version. I’m not crazy sure what the difference is between the two other than searching here a lot of people prefer the XFX but many were older threads.
XFX is 469 and Gigabyte is 489 so I’m not going to notice $20.
It will be paired with a Ryzen 5 7600X.
Input is much appreciated. I’m looking to stay under $550 total (tax included) so I’m open to other options. I plan to stick to this until it craps out or I just cannot play a game decently with it, not a quick future upgrade. I’ve used the 580 since 2020 to give a reference there, still works great but the there’s a need for 2 computers now.
submitted by SnakeDoctor00 to buildapc [link] [comments]
2024.11.25 23:50 Annoyed-Agent-8625 Got my violet team ready to go
Finally hatched the last shiny I wanted for my violet playthrough took 4 weeks at 1-2 hours a day. submitted by Annoyed-Agent-8625 to PokemonScarletViolet [link] [comments] |
2024.11.25 23:50 peytonloftis How to Clean Kitchen Faucet
Can anyone give me advice on how to clean this kitchen faucet? It is my mom's. She has been disabled & unable to clean for a while so I'm trying to help her. Hoping to not have to buy a new one. Thanks in advance! submitted by peytonloftis to Cleaningandtidying [link] [comments] |
2024.11.25 23:50 braki888 More tower concepts
This is an expansion on my last tower designs: https://www.reddit.com/kingdomrush/comments/1df0h5z/i_draw_some_my_own_towers/ Sylvan mage: Sylvan mages are the friends of the forest. They live in the deep forest and study the power within nature. However, when they sense an approaching threat to their home, they will return it with nature's relentless force. (As a mage barrack they deal magic damage and poison potions to the enemies. They can also use the force of the earth to reduce the percentage damages to protect themselves) Steam boy T45: Old style but new technique! This steam war factory shoots high-pressure cannon balls that leave steam for a few seconds to grill the enemies! (It can release steam to the enemies around the tower, dealing true damage and slowing them for a few seconds. The steam power also can activate a steam-flying droid as an extra small artillery to attack the enemies near the tower. The steam core inside the machine can hold high pressure and increase the steam damage when you level up the abilities. ) Sentinel’s bastion: Iron Sentinel order is the armor troops of an iron foundry country in the mountains. They are specialized in crafting iron weapons and armor. As an ally country to the Linirea, their king is willing to send his best troops to join in this crisis. Mystic spell caster: These fanatics manipulate a dangerous power of destruction. Their spells can tear up the space and shatter the enemies into pieces. Of course, many of them turn themselves into ashes in their way of pursuing this power. At first, they were just ecstatic about the energy flowing through their bodies. But when their bodies can no longer handle this power, it will also be their end day. It’s hard to say these madmen’s loyalty since they follow Vez’nan to seek his greater power. submitted by braki888 to kingdomrush [link] [comments] |
2024.11.25 23:50 Fit_Cycle_958 Lispy bitch: "I support straigjt people" .. WTF ?! Hahahah
submitted by Fit_Cycle_958 to fishtanklive [link] [comments]
2024.11.25 23:50 Zzzzz103 Good enough for champs??
Here is my current team up to date. I still do not think it is good for champs. I feel like a lot of teams already have a top 6 of all 86+.
Next Gen Event: what are you guys doing for the next gen event? Are you making any of the 86 cards? I want to make the Barzal or Kirill but they are just so expensive
submitted by Zzzzz103 to NHLHUT [link] [comments]
2024.11.25 23:50 Noledgebase Up and Running with NodeJs with Certification ($19.99 to FREE)
submitted by Noledgebase to Udemies [link] [comments] |
2024.11.25 23:50 lemkowidmak @NHLFlyers: 💜💜💜#HockeyFightsCancer | @Toyota https://t.co/Bkz0HjwSPd
submitted by lemkowidmak to phillysports [link] [comments] |
2024.11.25 23:50 Exotic-Panda- 💙🙏🙏💙
submitted by Exotic-Panda- to ScammingKevinDHughes [link] [comments] |
2024.11.25 23:50 Zestyclose_Sense_988 Im tweaking what does he say here
submitted by Zestyclose_Sense_988 to fuseboxgames [link] [comments] |
2024.11.25 23:50 RoleplayXAltXAccount [F4M] Fandom Roleplay ♡ Discord ♡ OC X CC ♡ Smut ♡ Long Term
Hola! I’m Kassie, I’m 26 years-old, I work from home and I absolutely love writing. I am autistic and have ADHD, but that doesn’t stop me too much from my writing. I’ve been roleplaying since I was 13, so I have a lot of writing experience. I am basically married, so nothing more than roleplaying for me!
┏━✦❘༻Looking For:༺❘✦━━┓
2024.11.25 23:50 Codingwithmr-m Need suggestions
Hi guys, I’m planning to buy the above model for my coding.
I’m a front end dev. Code a lot , run llm multiple tabs open on multiple browser plus multiple applications running background as well as I do edit videos for my yt content.
Is it gonna be enough for my work or do I need to go for other variants?
If you’re already using this model for the work I do. What’s your experience with that
submitted by Codingwithmr-m to macbookpro [link] [comments]
2024.11.25 23:50 Matt0975 [USA-MA] [H] 2021 M1 Pro 14” MacBook Pro Silver [W] PayPal
For sale is a 2021 M1 Pro 14” MacBook Pro Silver with the 8 Core CPU and 14 Core GPU.
AppleCare+ Valid until September 2025
Photos: https://imgur.com/a/0VLohJU
Repairs: None
submitted by Matt0975 to appleswap [link] [comments]
2024.11.25 23:50 QueenEle_96 Invited to shower but not the wedding-just venting.
submitted by QueenEle_96 to CharlotteDobreYouTube [link] [comments]
2024.11.25 23:50 Noledgebase Android Training and Certification - 49 Projects ($34.99 to FREE)
submitted by Noledgebase to Udemies [link] [comments] |
2024.11.25 23:50 lulublueblue8 looking for a roommate in lower manhattan
23F looking for a roommate/s (preferably female and around same age) in lower manhattan (i really like east/west village, hell's kitchen, chelsea, etc.) i work remotely so i would do that in my room during the day. my budget is around $1800/month each. i like going out but also staying in.
submitted by lulublueblue8 to NYCroommates [link] [comments]
2024.11.25 23:50 PurpleWitch333 Wanna be friends???
98QKK2X7PX is my code
submitted by PurpleWitch333 to finch [link] [comments]
2024.11.25 23:50 Commercial-Egg-1069 Dear flat earthers....
Good theory, ONE SMALL ISSUE
WHY, WOULD A GROUP OF PEOPLE, COME TOGETHER, AND SAY, HMMMM IM GONNA MAKE AN ORGANIZATION DEDICATED TO LYING ABOUT THE PLACE WE LIVE ON?? IT DOESNT MAKE SENSE!! YOU THINK THEY MADE THE EARTH?? DO YOU THINK THEY MADE IT FLAT??? OF COURSE YOU DONT. AND YOU IGNORE EVERY PICTURE THAT IS THROWN YOUR WAY, "ITS A FISH EYE LENS" OR "THEY ARE LYING TO YOU" GODDAMN THEY ARENT, THERE ARE COUNTLESS IMAGES BEFORE NASA WAS EVEN INVENTED, AND YOU IGNORE THE USSR, AND EVERY OTHER AGENCY, OHH YEAH I FORGOT, BECAUSE APPARENTLY THEY DONT EXIST!!!! APPARANTLY THE WORLD IS ONLY MADE OF CHINA, EUROPE, AND THE AMERICAS, AND HOW THE HELL DO YOU NOT REALISE, EVERYTHING HAS GRAVITY, THE BIGGER THE OBJECT IS THE MORE GRAVITY IT HAS DUMB###, THERE ARE REAL EXPERIMENTS TO PROVE THIS, THE ONLY REASON THAT WATER DOESNT STICK TO A BALL WHEN YOU POUR IT ON IT, IS BECAUSE THE EARTH IS THE ONE WITH GRAVITY, A MEASLY FREAKING BALL IS NOT ENOUGH MASS TO GIVE OFF A FIELD, HOW IS SOMETHING THAT TOOK HUMANS YEARS TO ADVANCE TO EVEN KNOW, STILL SO INCOMPREHENSIBLE, THE EARTH IS (12,760 kilometers) BIG, YOURE STILL GONNA FIND A WAY TO SCAPEGOAT ME, YOU'LL FIND A WAY TO "PROVE" IM "LYING", YOU DONT BELIEVE ANYONE, YOU DONT TRUST ANYONE, BECAUSE OF IGNORANCE, PEOPLE TAKE YEARS OF EFFORT JUST TO DISCOVER THINGS, AND FOR WHAT, SOME TRACTOR LOVING TINFOIL HAT WEARER TO TRY AND MAKE THEM LOOK BAD??? AM I A LIZARD MAN FROM THE FREAKING ILLUMINATII? WHY, WOULD THEY HAVE A REASON, TO LIE?? THE EDUCATION SYSTEM HAS FAILED YOU, OR WAIT... YOU THINK THEY'RE LYING, YOU DONT TRUST ANYONE, YOURE JUST PARANOID AND IGNORANT!!!! submitted by Commercial-Egg-1069 to BallEarthThatSpins [link] [comments]
2024.11.25 23:50 Noledgebase iOS, Android and Web Application Training - My Instagram App ($19.99 to FREE)
submitted by Noledgebase to Udemies [link] [comments] |
2024.11.25 23:50 th3thrilld3m0n Got some Hololive prizes from Round1!
submitted by th3thrilld3m0n to vtubers [link] [comments]
2024.11.25 23:50 Smokey_ashes0607 Question about fry screaming
I have been trying to learn to fry scream but I just cant get it down. I have the false cord noise down but any time I try to fry scream it just sounds like a high pitched growl. If anyone has any tips can you help me please
submitted by Smokey_ashes0607 to screaming [link] [comments]
2024.11.25 23:50 Superb-Citron-8839 കഴിഞ്ഞ 24 മണിക്കൂറിനുള്ളില് അദാനിയുമായി ബന്ധപ്പെട്ട വാര്ത്തകളാണ് ഇതോടൊപ്പമുള്ളത്.
കഴിഞ്ഞ 24 മണിക്കൂറിനുള്ളില് അദാനിയുമായി ബന്ധപ്പെട്ട വാര്ത്തകളാണ് ഇതോടൊപ്പമുള്ളത്. ഫ്രഞ്ച് ഓയില് കമ്പനിയായ ടോട്ടല് എനര്ജീസ് അദാനിയുമായുള്ള ബിസിനസ് ബന്ധം താല്ക്കാലികമായി നിര്ത്തുകയാണെന്ന് അറിയിച്ചിരിക്കുന്നു. അദാനി ഗ്രൂപ്പുമായുള്ള നിക്ഷേപ മേഖലയിലെ സാമ്പത്തിക ഇടപാടുകളും അവസാനിപ്പിക്കുകയാണെന്നാണ് ടോട്ടല് എനര്ജീസിന്റെ പ്രഖ്യാപനം. അടുത്തത് അദാനിയുടെ ശ്രീലങ്കന് പദ്ധതിക്കുള്ള സാമ്പത്തിക സഹായം നല്കുന്ന അമേരിക്കന് ഡെവലപ്പ്മെന്റ് ഏജന്സി അദാനിക്കെതിരായ കൈക്കൂലി കേസില് വ്യക്തത വരുന്നതുവരെ പദ്ധതിക്കുള്ള സാമ്പത്തിക സഹായം നിര്ത്തിവെക്കുകയാണെന്ന് പ്രഖ്യാപിച്ചു. മൂന്നാമത്, ബംഗ്ലാദേശ് സര്ക്കാരിന്റെ വകയാണ്. ഷേയ്ഖ് ഹസീനയുടെ കാലത്ത് ഗൗതം അദാനിയുമായി ഉണ്ടാക്കിയ പവര് സപ്ലൈ കരാറുകള് സംബന്ധിച്ച് അന്വേഷണം നടത്താനാണ് യുനുസിന്റെ നേതൃത്വത്തിലുള്ള സര്ക്കാര് തീരുമാനം. ഇന്ത്യയുമായുള്ള ഉഭയ കക്ഷി ബന്ധത്തിന്റെ പേരില് എല്ലാ പദ്ധതികളും അദാനിക്ക് നല്കുക എന്നതായിരുന്നു ഹസീനയുടെ നയം. ഈ പദ്ധതികളെല്ലാം പുതുതായി നടക്കുന്ന അന്വേഷണത്തിന്റെ പരിധിയില് ഉള്പ്പെടുമെന്നാണ് അറിയുന്നത്. അടുത്തത്, ഇന്ത്യയില് നിന്നുതന്നെയാണ്. അദാനിയുടെ 100 കോടി രൂപയുടെ സംഭാവന വേണ്ടെന്നാണ് തെലങ്കാന സര്ക്കാരിന്റെ പ്രഖ്യാപനം. കാര്യങ്ങള് ഇങ്ങനെയൊക്കെയാണെങ്കിലും........ ഒരുകാലത്ത് വിഴിഞ്ഞം ഭൂമി ഇടപാടില് 6000 കോടിയുടെ അഴിമതി ഉന്നയിച്ചവരില് നിന്ന് ഒരു മൂളക്കംപോലും ഉയരുന്നില്ലെന്ന കാര്യം അദാനിയെത്തന്നെ അത്ഭുതപ്പെടുത്തിയെന്നതാണ് വസ്തുത. ഹിന്ഡന്ബെര്ഗ് റിപ്പോര്ട്ട് തൊട്ട് അദാനി സാമ്രാജ്യത്തിന്റെ ചതിക്കഥകള് ഒന്നൊന്നായി പുറത്തുവന്നിട്ടും രാജ്യത്തെ പ്രതിപക്ഷ രാഷ്ട്രീയ പാര്ട്ടികള് ഒന്നും തന്നെ പ്രക്ഷോഭവുമായി തെരുവുകളിലിറങ്ങുന്നില്ലെന്ന കാര്യം പ്രത്യേകം ശ്രദ്ധിക്കേണ്ടതാണ്. കോണ്ഗ്രസ്സില് രാഹുല് ഗാന്ധിയും തൃണമൂല് കോണ്ഗ്രസ്സില് മഹുവാ മൊയ്ത്രയും ആം ആദ്മിയില് അരവിന്ദ് കേജ്രിവാളും വ്യക്തിപരമായി പ്രതിഷേധ സ്വരങ്ങള് ഉയര്ത്തുമ്പോഴും തങ്ങളുടെ അണികളാരും തന്നെ ഈ വിഷയമുന്നയിച്ച് തെരുവിലിറങ്ങരുതെന്ന് പ്രത്യേക നിര്ദ്ദേശം നല്കിയതുപോലെയാണ് കാര്യങ്ങളുടെ പോക്ക്. അദാനി എന്ന മൂന്നക്ഷരം ഉച്ചരിക്കാൻ ഇന്ത്യയിലെ രാഷ്ട്രീയ പാര്ട്ടികള് ഭയക്കുന്നതെന്തിന്?!! K Sahadevan https://preview.redd.it/l99gnalox43e1.png?width=945&format=png&auto=webp&s=023404ff7370fb1e47aaf1c830965287848926b7 https://preview.redd.it/fn0iob1qx43e1.png?width=975&format=png&auto=webp&s=b8ae1c705b6cea4f8e685a9fe38d5ef3e5e00258 https://preview.redd.it/2iz16r6rx43e1.png?width=1112&format=png&auto=webp&s=df38d5e89e1a8826150f599a920083a914669d14 https://preview.redd.it/dl64hzdsx43e1.png?width=690&format=png&auto=webp&s=97feb42144ad253db1afe8bf20ba9e7b49473d39 submitted by Superb-Citron-8839 to YONIMUSAYS [link] [comments] |
2024.11.25 23:50 Sajr666 LF Galactus
LF Galactus Golden Blitz FT Orb of Agamotto looking for dice so I can try and complete side event for purple pack. 1 of 2 gold needed to complete a set. 160/162. https://mply.io/wy9lTg submitted by Sajr666 to monopolygo_fairtrade [link] [comments] |
2024.11.25 23:50 10KBC Make sure you have a high bounty when you go to Military Fort of Gla, so Pater can help you dispose of the mercenaries :)
submitted by 10KBC to AssassinsCreedOdyssey [link] [comments] |