New Members Intro
2024.11.25 02:30 GlassIndependent7259 New Members Intro
If you’re new to the community, introduce yourself! and enjoy the ARG
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2024.11.25 02:30 FlyingSoapDispenser Depression and Slow COMT: what am I supposed to do in terms of dopamine production/breakdown?
Calling all psychiatrists knowledgeable in the methylation cycle, especially COMT!
I have struggled with depression/anxiety my whole life (and possibly ADHD?), and I know I have the slow COMT (met/met) gene. I'm aware that this means my brain has a hard time processing dopamine and other catecholamines.; everything I read online says slow COMT people suffer from too high dopamine levels as a result. But I'm also seeing that people who have depression, as one would expect, feel depressed and unmotivated due to a LACK of dopamine. So how exactly does slow COMT relate to depression? Does that mean that I have an excess amount of dopamine floating around in my brain, and my body can't do anything with it? That it's only useful when broken down? If so, how do I speed up the dopamine processing process? I'm also confused if this means I should be doing more to actually produce dopamine, or if my brain produces a sufficient amount and just needs help getting rid of it, or both?
Also, my psychiatrist wants to add Wellbutrin to my SSRI dose, since my SSRI has stoped being effective. But if my body already has enough dopamine, wouldn't it be counterintuitive to take meds that keep dopamine in the brain longer?
I've been having such a hard time finding a doctor who can actually explain this whole slow COMT thing to me and treat my depression accordingly. And google searching isn't answering my questions sufficiently. What meds or supplements should I be taking? How do I facilitate the dopamine issue? So far I've just gleaned that I shouldn't be taking "methylated" vitamins (but I also have a bad MTHFR if that's helpful).
TL;DR What is a person with depression and slow COMT supposed to do for their dopamine levels?
submitted by FlyingSoapDispenser to MTHFR [link] [comments]
2024.11.25 02:30 DivideAdditional5371 Under 21 apps?
an sports betting apps for users under 21?
submitted by DivideAdditional5371 to sportsbetting [link] [comments]
2024.11.25 02:30 Flimsy-Sound-8149 Can anyone help me :-)
 | Play MONOPOLY GO! with me! Download it here: https://mply.io/-fPpmQ submitted by Flimsy-Sound-8149 to Monopoly_GO [link] [comments] |
2024.11.25 02:30 2009miles This bitch seriously trying to get 10k out of Sam just to start an argument?
submitted by 2009miles to fishtanklive [link] [comments]
2024.11.25 02:30 TheFunkySpaceman UPDATED -- Review of the NQID 60 LED dual-chip 660/850 panel -- now with flicker, spectrum, more
After posting this review, I made an update with flicker assessment, and just now I took spectrometer and power readings, so I thought a repost with the new info was merited.
Intro
This red light panel from NQID first caught my eye due to a pair of stacking discounts making the final price just $42. That deal has since expired, but it had some other discount every time I have looked. It is currently down to about $70 right now for Black Friday 2024.
https://www.amazon.com/dp/B0D3LWGBGL
These are the listed features:
- 60 dual-chip LEDs (power unlisted)
- 660 nm & 850 nm light
- Wattage is unspecified, but it listed irradiance values on par with similar panels from other makers.
- MSRP $150 but I have seen it as low as $42, and for Black Friday it's $69.
The case is metal and feels sturdy enough. The kickstand is somewhat flimsy... But, good enough. The control panel is ... Fine. I have had no problems operating the unit, except that it is too easy to touch the touchpad if you are holding it on your lap.
The fan is pretty quiet. I did not measure it, but it's quiet enough that I don't even think about it.
Overall, this panel is sturdy and well-made enough that I haven't had any second thoughts in my few weeks of ownership.
Flicker Assessment
I tried to detect flicker using my phone camera, and could not find any. If I waved my hand around in front of the light, there were no obvious motion trails like you see with badly flickering LED lights.
I then built a simple photodiode circuit and hooked up an oscilloscope. This clearly showed the presence of a 120 Hz pattern.
https://i.imgur.com/at2Q2CB.jpeg
So, these LEDs are flickering -- but with this crude test and dumb scope, I cannot calculate the flicker percent. If we look at the scope we can see that the voltage is above zero for most of the cycle, but that's not saying much.
https://i.imgur.com/zre4rJL.png
Overall, I give this light a pass on flicker though I want to refine this test method.
Spectrum Assessment
I ordered a Little Garden spectrometer to use for this assessment. It's a cheap instrument, but it's good enough to let you verify a panel manufacturer's claims.
Here's the spectra of the red LEDs. The manufacturer claims 660 nm. I measured 661 nm, which is within the margin of error of my spectrometer.
https://i.imgur.com/B7WxRAw.png
The near-infrared LEDs are rated at 850 nm, and I measured a peak at 852 nm. Again, that's on target within the limitations of the instrument.
https://i.imgur.com/Ub0luhb.png
Overall, the manufacturer's ratings seem credible.
Irradiance Assessment
As we all know, the manufacturer's irradiance values can be inflated. After using the panel while assuming that the OEM values were probably 2x the true values, I decided to get a meter and see for myself. I got the Tenmars TM-206 solar power meter and used the correction calculators provided by GembaRed.
https://gembared.com/blogs/musings/budget-intensity-measurements-for-red-light-therapy-part-1-of-3-tenmars-tm-206
Basically, the rule of thumb that the manufacturer's values are twice the real values is in the right ballpark.
Overall, I rate the irradiance as passing, with the usual caveats that you cannot really trust the OEM numbers.
(I will provide the raw data and some charts that may be useful for anyone else who buys this panel. You can use the charts to figure out the distance needed for the irradiance you want.)
Power Draw
A Kill-A-Watt device showed these values.
- Red + NIR: 90 W
- Red alone: 57 W
- NIR alone: 39 W
- Idle: <= 2 W
I didn't try the door hanger, but it looked credible.
The green safety glasses were nothing special. They are pretty big, too, and if you are trying to treat bags under your eyes, they will cover that area. The safety glasses didn't come with an FDA rating, though. How good are they, really?
Here is the spectra of the panel with both LEDs on.
https://i.imgur.com/2zEFGtO.png
And here's the same thing, but looking through the safety glasses.
https://i.imgur.com/El3KtGF.png
So, the glasses do seem to be effective at dimming the red light. They don't hamper the NIR at all.
Personally, I still found the red light to be too bright through the glasses and closed eyes when treating my face, and bought some smaller, darker green glasses. These won't obscure the skin under my eyes, either.
Customer Support
I had a problem with the remote control that came with the unit... It required a pairing process, but when I followed the instructions, things didn't happen as the instructions said they should. I contacted tech support over email and within a day they had sent me some new instructions, which did work. So, I rate NQID's support as good so far.
Does RLT Work?
Hard to say, honestly. I have only been doing it for a few weeks. Still, I think that it is fair to say that skin blemishes have been less frequent, smaller, and subside more quickly. Time will tell if there are other benefits.
Final Verdict on the NQID 660/850 panel
This panel provides 660 nm and 850 nm light as promised. The irradiance is half what they claim--but almost every other manufacturer has the same problem. But even at half the listed power, it has enough power to be therapeutic. For example, to treat my face, holding it in my lap at 18-20" away is about 35 mW/cm2, which is just right. For me, anyway.
At the MSRP of $150 it seems like a reasonable option. But, if Amazon is running any big discounts that take it below $100, then this panel from NQID seems like a very good deal.
Irradiance measurement setup
https://i.imgur.com/JVXH5yy.jpeg
Table of values
https://i.imgur.com/l7h9ijT.png
Chart with exponential fit
I use this chart as a quick powedistance reference.
https://i.imgur.com/pWCVvzd.png
Here is a chart zoomed in on the more useful region. Remember that the purple line is combined power, the red line is just 660 nm and the grey line is just 850 nm.
https://i.imgur.com/vdQtOGr.png
Data
If you want to do your own analysis, here is the raw data. You will notice that at one point, the irradiance goes up slightly with increasing distance. That's not an error, it has to do with how the LEDs overlap. You don't get into a tidy inverse square situation until you get farther away from the panel.
The manufacturer does claim that the two kinds of LEDs are in a "balanced 1:1 ratio." That's clearly not the case when you consider irradiance, with the red lights producing more than half the output.
https://pastebin.com/Ct4gxNct
submitted by TheFunkySpaceman to redlighttherapy [link] [comments]
2024.11.25 02:30 AutoModerator ఈ వారం ఊర పంచాయతీ - Day of November 25, 2024
ఉచిత సలహాలు, పిచ్చా పాటి కబుర్లు, సినిమా విశేషాలు, రాజకీయాలు.. అన్ని మాట్లాడుకోండి.
submitted by AutoModerator to Ni_Bondha [link] [comments]
2024.11.25 02:30 throwawayhouseseller I googled "churches in Loveland" to come up with the top 10 most "popular" churches in town. I then found each church's lead pastor's house value on Zillow. Conclusion: being a pastor appears to be a wise career choice if you desire to live in above-average (and in some cases, lavished) housing...
 | submitted by throwawayhouseseller to loveland [link] [comments] |
2024.11.25 02:30 Sea-Country482 Cd unknown DPO Unknown
 | Period is late late and I had pink discharge for 5 days about 10 days ago. Only when I wiped not enough to get a pad. then nothing. Took this test and literally with in a minute I swear I see a line. Can anyone else see it or am I going crazyyyy! submitted by Sea-Country482 to TFABLinePorn [link] [comments] |
2024.11.25 02:30 AutoModerator Monday Megathread! Ask questions and share knowledge; newcomer questions encouraged!
Welcome to the latest Monday Megathread, where you the community get to ask your questions and share your knowledge.
Need help against a certain champion? Unsure how and where to ward? Looking to improve your csing? This is the place to ask. This weekly thread is a place for new players to ask questions and get help/advice from more experienced players. So, don't hold back, get your game related questions ready and post away, and hopefully someone can answer them!
Previous threads
Looking to chat with people live? Come check out our discord channel here! We also have the channel #new-player-help if you want to ask questions there.
If you are willing to learn, /SummonerSchool and its respective discord are always willing to teach.
New Player Guide by The-All-Tomato
Riot's New Player Guide
LolEsports New Viewer Guide
Other:
Please sort this post by new, so that you can see the newer, unanswered questions.
submitted by AutoModerator to leagueoflegends [link] [comments]
2024.11.25 02:30 __aqen__ Trip Itinerary Opinions
Hey everyone, a first time traveller to Puerto Rico here. I've planned a tentative itinerary but wanted some opinions before book everything. The flights are booked (landing in SJU on the 15 th of December and Departing on the 23rd of December). Feel free to recommend / dissuade me from anything on here or suggest new things. Thanks.
Day 1-15th Travel to SJU
Day2-16th SJU city/vicinity sightseeing
Day3-17th SJU and old sightseeing
Day4-18th El. Yunke National Park
Day 5-19th Vieques (option Fajardo in the morning)
Day 6-20th Return to main island and travel west (option El Yunke in the afternoon)
Day7-21st Sandra Coffee Farms/Cueva ventana and Cueva indigo
Day 8-22nd Long drive on coast/explore non touristy beaches
Day9-23rd Travel back to SJU... flight departs ~4pm
submitted by __aqen__ to PuertoRicoTravel [link] [comments]
2024.11.25 02:30 zealsupport Men Clothes Dior Sweater - https://www.zealrep.pl/index.php?main_page=search_result&search_in_description=1&keyword=Dior+Sweater
 | submitted by zealsupport to zealrep_pl [link] [comments] |
2024.11.25 02:30 sharewithme WoTH: Vocabulary Quiz - Day 1543 Morning
See words and translations for the past 24 hours below.
| English | French | German | Italian | Portuguese | Spanish |
|---|---|---|---|---|---|
| grave | grave | Missing? | tomba | túmulo | tumba |
| shore | Missing? | die Küste | riva | litoral | orilla |
| between | entre | zwischen | fra | entre | en medio de |
| awkward | étrange | unangenehm | incomodo | constrangedor | incómodo |
| captain | capitaine | der Kapitän | capitano | capitão | capitán |
| rapidity | rapidité | die Schnelligkeit | rapidità | rapidez | rapidez |
| best | meilleur | bestebeste/bestes; dedie/das Beste | più | (o/a/os/as) melhor(es) | más |
| moderate | modéré | mäßigt | Missing? | moderado | moderado |
| bent | incliné, plié | gebogen | piegato | curvado / dobrado | doblado |
| approximate | approximer | schätzungsweise | Missing? | aproximar / aproximado | aproximadamente |
| terrestrial | terrestre | Missing? | terrestre | terrestre | terrestre |
| bottle | bouteille | die Flasche | bottiglia | garrafa | botella |
Thank you for all of your help and support!
submitted by sharewithme to Word_of_The_Hour [link] [comments]
2024.11.25 02:30 Asuna0506 Switching from Adderall IR to Dexedrine - dose confusion
It’s a long story, so I’m just going to leave out any unnecessary details. (Yes I’ll be speaking with doctor tomorrow, and no I won’t change anything until she gives the “okay” etc.)
- Was recently prescribed generic Dexedrine (dextroamphetamine) 15 mg - blue oval tablets. Are these IR or ER?
- I usually take generic Adderall IR 30 mg. I am aware of the differences between these two medications (and the similarities) and that it’s impossible to do an EXACT conversation with dosages, but I’m wondering if there’s at least an approximate number?
I’ve searched everywhere for an answer to this, but anything related is always referring to Adderall XR.
(Also, I’ve taken the 15 mg Dexedrine before, and it felt like I hadn’t taken anything at all)
submitted by Asuna0506 to Narcolepsy [link] [comments]
2024.11.25 02:30 Ab501ut3_Z3r0 There are only two light subclasses with a single option for an ability
Void hunter and void warlock are the only light subclasses with any abilities that have only a single option. Namely, they each only have a single melee (smoke bomb and pocket singularity respectively). While the darkness subclasses obviously all have one option for melees and supers, these two are unique among the light subclasses. It would be great to give these some of the melee variety that the other 7 light subclasses all have.
submitted by Ab501ut3_Z3r0 to DestinyTheGame [link] [comments]
2024.11.25 02:30 CakeofRivia [FOR HIRE] NSFW Artist available to work, you can DM me if interested~
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2024.11.25 02:30 Better-Database1209 F23
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2024.11.25 02:30 AutoModerator Kleine wöchentliche Fragen Thread - KW 48
Du hast eine kleine Frage?
Es gibt keine dummen Fragen, nur dumme Antworten. Wer nicht fragt, bleibt dumm. Wer fragt, ist ein Narr für eine Minute. Wer nicht fragt, ist ein Narr sein Leben lang.Poste hier deine Fragen, die dir zu lang für einen ganzen Thread erscheinen oder du nur eine kurze Antwort erwartest. Dabei gibt es auch in der Technik-Welt viele Dinge die nicht jeder wissen kann.
Dieser Thread ist nach neuen Posts sortiert. Archiv
Alternativ steht euch auch das Discord zur Verfügung.
submitted by AutoModerator to de_EDV [link] [comments]
2024.11.25 02:30 barfytarfy Why are people in St. Charles flying the Betsy Ross flag now?
Is it because they want us to go back to when only white landowning men voted and slavery was legal?
submitted by barfytarfy to StCharlesMO [link] [comments]
2024.11.25 02:30 BroMandi [Amazon] $14.98: Castle Panic 2nd Edition Cooperative Board Game at Amazon [Deal: $14.98, Actual: $34.95]
![[Amazon] $14.98: Castle Panic 2nd Edition Cooperative Board Game at Amazon [Deal: $14.98, Actual: $34.95]](https://preview.redd.it/6ro87u5dly2e1.jpeg?width=320&crop=smart&auto=webp&s=603f74b221e82e2e747cf223aa2b436ec24cd7c9 "[Amazon] $14.98: Castle Panic 2nd Edition Cooperative Board Game at Amazon [Deal: $14.98, Actual: $34.95]") | submitted by BroMandi to RedditShoppingDeals [link] [comments] |
2024.11.25 02:30 sploucheneige Is the Ride Kink too soft for all mountain riding and trees?
I want a soft board to get better in the park, but i still want to be able to follow my friend and go fast
submitted by sploucheneige to snowboardingnoobs [link] [comments]
2024.11.25 02:30 TusharG-Packt Jet/Power washer suggestions needed to clean Grime (UK)
 | Hi, Can someone recommend a good Jet/Power washer which will help in getting rid of this grime? Or, is it cheaper to call a professional? How much would they charge? submitted by TusharG-Packt to CleaningTips [link] [comments] |
2024.11.25 02:30 car_eater2684 Jorge Be Like:
 | submitted by car_eater2684 to Epicthemusical [link] [comments] |
2024.11.25 02:30 idonthaveacow Do I even apply?
I want to go to my state school that has an 80%+ acceptance rate. I have a 4.0 GPA, am in early college, and have a lot of college credits. I'm going test optional (1300 on the SAT). I have about 120 volunteer hours related to my careemajor, 30ish unrelated hours, ~400 paid work hours related to my careemajor, and like 90 job shadow hours. I don't have any leadership or research or anything impressive at all. I don't even play a sport. I'm feeling doomed.
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2024.11.25 02:30 AmrTGC What is this?
This post contains content not supported on old Reddit. Click here to view the full post
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