ts should be a dark ops bro
2024.11.28 10:40 MrBreakkZ ts should be a dark ops bro
 | i can't describe how freakin hard this was and how much time I've put into this only challenge. it's crazy how bad molotovs in this game are but at least thermo grenades are somewhat decent https://preview.redd.it/vqri1rvefm3e1.png?width=657&format=png&auto=webp&s=df924ea28896eae03360a02cbd277e3dbffa41d7 submitted by MrBreakkZ to blackops6 [link] [comments] |
2024.11.28 10:40 threenintytwo What tf (the fuck) is his name? And why tf (the fuck) is it looking for man?
 | submitted by threenintytwo to BatmanArkham [link] [comments] |
2024.11.28 10:40 MasquedCurio Health Effects of 33 mtDNA gene deletions
Hello, I’m posting in hopes of getting some input from people better versed in this subject than I am.
*please note- I’ve been given explicit permission to seek advice and opinions on this matter on behalf of my mother, but as this is a genetic issue that may also affect myself, I am also asking to gauge potential risks for my own future health
My mother has been struggling with many health issues and they’ve been getting worse. She was diagnosed with Mitochondrial Myopathy a year ago following a muscle biopsy. She has since had her genome sequenced.
Following a consultation with a geneticist, we’ve learned she has 33 gene deletions in her mtDNA. We think this is what has been causing most of her major issues.
The doctors (genetics, neuro, endocrine, etc) have mostly just been putting her on supplements and medications, but nothing seems to be working.
I have a few questions and ideas.
1) since mtDNA is often passed down maternally, what’s the chance that me and my siblings + their kids may have these same mutations? I don’t expect a specific % chance, but it would be nice to know a ballpark range.
2) since mom is suffering from genetic issues, is it possible that in the coming years CRISPR or other gene therapies could be used to repair her dna? Is this something worth talking to her doctors and specialists about? Or is it a distant possibility?
3) I’ve been reading on other forums and sites about people who have had some anecdotal success with other supplements, but I’m skeptical of both safety and efficacy. Is there anything she should try if the prescribed or recommended supplements dont help?
4) would lifestyle changes help improve symptoms? She finds it incredibly hard to breathe, walk, or lift anything. She struggles just picking up a 5lbs dog or walking from her bedroom to the kitchen. She has been doing physical therapy for the better part of a year, but only seems to be getting worse. To me it seems like her muscles are atrophying following use because her cells cannot meet the energy demands and so the cells may be dying.
5) would her digestive issues potentially be caused or worsened by mitochondrial myopathy? Since digestion is such an energy intensive process, is her inability to make ATP what causes a slowed metabolism, lots of nausea, and could it worsen IBD?
6) I’ve been having more and more health issues of my own the last few years. Starting with PCOS (diagnosed) and symptoms of POTS, CFS, and Hashimotos (things that others in my family are effected by) but I’ve been having other issues arise, especially the last two years. I’m 20 and had to have my gallbladder out this past May due to biliary dyskinesia. Only some of the symptoms have been alleviated and I still often have pain and nausea. I’ve had increasing fatigue and my metabolism has seemed slower and more inconsistent. I am wondering if I could possibly be showing signs of the same diseases affecting my mother? Especially mitochondrial myopathy, since I seem to be having similar early symptoms as my mom did and it does likely have a genetic component. My mom thinks I should also get my genome sequenced, but with the amount of money it costs, I’m not sure if it is necessary at this point.
Thank you for taking the time to read this. Any insight, no matter how minor, is deeply appreciated. I know there aren’t any miracle cures or easy answers to any of these, but just knowing that I can help her find something, or help the doctors think outside the box, would be worth it to us. Even just knowing that some of my ideas are on the right track would be so so helpful in helping us find the right questions to ask her doctors or finding the right places to look for treatment possibilities.
submitted by MasquedCurio to medical_advice [link] [comments]
2024.11.28 10:40 Seasoned_Flour What is this?
This post contains content not supported on old Reddit. Click here to view the full post
submitted by Seasoned_Flour to Pixelary [link] [comments]
2024.11.28 10:40 xigxagxoe For the first time in history, PSX crosses 100,000 points. Bad news for miscreants
 | submitted by xigxagxoe to PAK [link] [comments] |
2024.11.28 10:40 Accomplished_Idea222 Jemand aus Nähe Darmstadt ( Pfungstadt, Bickenbach,Seeheim,Eberstadt) und will über IRLs schreiben
 | submitted by Accomplished_Idea222 to Snapchatgerman [link] [comments] |
2024.11.28 10:40 DustyWorker I want my girlfriend, 5ft tall with tiny hands, to buy a handgun for self defense and home security. Options?
Currently I think a Sig Sauer p365 would be perfect for her hands, as well as being a reliable firearm.
What other compact 9mms with these factors of importance, listed in order, would be great choices
- Reliability
- Accuracy before mods
- Recoil before mods
- Price
- Ammo capacity
2024.11.28 10:40 Gaypnp83 Fun
https://us06web.zoom.us/j/89789619986?pwd=sHPON2tnUIduXEN0A830hLl77Mndod.1
submitted by Gaypnp83 to gayzoomcomunity [link] [comments]
2024.11.28 10:40 TheBald_Dude Quantidade de cafeína dum café português normal?
Boas pessoal,
Tomo muitos cafés e queria diminuir o preço que gasto nestes. Normalmente tomo "café no café" e apercebi-me que ao preço que está se mudar para cápsulas poupo à volta de 2/3 do valor.
Mas tenho um problema, não sei qual é o equivalente em termos de quantidade cafeína entre um típico café português e as cápsulas. A confusão é ainda pior porque o número da cápsula está relacionado com a "intensidade" que não é exatamente proporcional à "quantidade de cafeína" na cápsula.
Se alguém que conseguir ajudar agradecia!😅
PS: Estou a pensar comprar cápsulas da Bicafé. Do que vi parecem ser as mais baratas.
submitted by TheBald_Dude to portugal [link] [comments]
2024.11.28 10:40 Due-Spread-9065 Of course we got mentioned on Twitter.
 | submitted by Due-Spread-9065 to hazbin [link] [comments] |
2024.11.28 10:40 Fuenf56 Death Korps Infantry Loadout(s)?
With the announcement of the plastic box I've dug out my fw squads and looked at the rules (they also need a repaint, sheeeeeesh).
What are your preferred loadouts for the infantry? I'm prolly gunna pop a medic in the squad and add a launcher and the plasma in 20 mens.
I'm aware it's very much 'take what you want' but it's nice to see what others take too!
submitted by Fuenf56 to Deathkorpsofkrieg [link] [comments]
2024.11.28 10:40 DizzyLizzard99 Which one
 | I have one card to spend before it's all over in a couple hours submitted by DizzyLizzard99 to ACPocketCamp [link] [comments] |
2024.11.28 10:40 hendogxx I need help
I need help getting projects from GitHub and bolt.new to run, I don't understand what I'm doing wrong
submitted by hendogxx to github [link] [comments]
2024.11.28 10:40 indpndntusagi Having trouble picking a new phone for a gift to myself
Hello! so i've been reading comparisons between 2 phones: Samsung A55 and Oppo Reno 12 5G.
I can say is medjo lamang si A55 by a few margins but affordability and performance habol ko haha i dont mind swiping the remaining amount but i have 25-26k budget ready and yet there are other brands competing like Xiaomi, Vivo and Huawei (if may google lang haha)
can you smack some sense ano maganda bilin? haha im not that techy
submitted by indpndntusagi to Tech_Philippines [link] [comments]
2024.11.28 10:40 nothingbutaspeck Any good LTF credit cards here?
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2024.11.28 10:40 Material_Ad_3794 Love’s last investment on NovelShort
submitted by Material_Ad_3794 to novelsfree [link] [comments]
2024.11.28 10:40 Jyhnne Best Bed Ever 🤤🤤🤤
submitted by Jyhnne to NikkeMobile [link] [comments]
2024.11.28 10:40 Objective-Ingenuity 241128 BABYMONSTER reachs 3 MILLION Followers on Spotify
 | submitted by Objective-Ingenuity to BABYMONSTER [link] [comments] |
2024.11.28 10:40 hoppema0180 Leren handschoenen wintersport
Hi allemaal,
Iemand goede tips voor BIFL handschoenen voor de wintersport? Binnenkort gaan we namelijk weer een weekje weg en helaas gaan mijn wat goedkopere handschoenen vaak kapot. Daarom ben ik nu op zoek naar leren handschoenen, welke een stuk minder snel worden open gesneden door de ski’s.
submitted by hoppema0180 to BIFLNL [link] [comments]
2024.11.28 10:40 Imaginary_Ad4527 secret note help
i have a secret note called ancient graveyard with a x on it but i have no idea where the ancient graveyard is, in event lookup there’s also a cut scene called ancient graveyard.
does anyone know where this location is? i have a feeling it’s from passerby cemetery or maybe east scarp i’m not sure.
submitted by Imaginary_Ad4527 to StardewValleyMods [link] [comments]
2024.11.28 10:40 Glum_Practice_4616 Recommendation for phone repair shop in Hoi An
Hello! I am currently traveling Vietnam and my phone broke on me and needs repairing. My battery has swollen and needs replacing. The thing that makes it tricky is that I have a Google Pixel 6, which is not available in Vietnam, so finding spare parts is going to be hard. I am currently in Hue but I'm leaving tomorrow for Hoi An, so I'd love to have a few recommendations of good shops before I get there so I can bring it to them immediately as it might take a while to order the parts. Thanks everyone!!
submitted by Glum_Practice_4616 to VietNam [link] [comments]
2024.11.28 10:40 RovJos Silky dark hair
 | submitted by RovJos to HairWeLike [link] [comments] |
2024.11.28 10:40 Eriol_Mits Transpennine express class 802 in action.
 | submitted by Eriol_Mits to trains [link] [comments] |
2024.11.28 10:40 Express-Produce4631 can you do a price check, please?
 | New condition submitted by Express-Produce4631 to NumberNine [link] [comments] |
2024.11.28 10:40 Middle_Locksmith8839 this sleepy employee needs a nap
 | submitted by Middle_Locksmith8839 to bodegacats [link] [comments] |