Scientists Uncover Hidden RNA Structure That Triggers Parkinson’s Disease
2024.11.27 14:40 ImSoOutofUsernames Scientists Uncover Hidden RNA Structure That Triggers Parkinson’s Disease
I hate to share another mice model study, but this is brand new and seems promising. ChatGPT summary:
Researchers have discovered that RNA structures called G-quadruplexes (G4s) promote the aggregation of α-synuclein, a protein linked to Parkinson's disease. Stress-induced calcium ion increases drive G4 formation, which acts as a scaffold for harmful protein clumps. In mice, the compound 5-aminolevulinic acid (5-ALA) blocked G4 formation, preventing protein aggregation and halting motor symptoms. This finding suggests a promising therapeutic target not only for Parkinson’s but potentially for other neurodegenerative diseases like Alzheimer’s.
Article: https://scitechdaily.com/scientists-uncover-hidden-rna-structure-that-triggers-parkinsons-disease/
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2024.11.27 14:40 aczemdone True Shot Gun Club Black Friday 2024 Offers
Follow this link for True Shot Gun Club Black Friday 2024 Offers. Access the latest deals and promotions by visiting the link, featuring a constantly updated list of coupons, promo codes, and discounts.
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2024.11.27 14:40 matt_iAM "Our holiday collection is officially live!"
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2024.11.27 14:40 Technical_Agent8481 With the new Rocka Rolla now out, and Sad Wings in production, which other artist/album do you think would benefit from the Tom Allom magic touch?
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2024.11.27 14:40 mycketforvirrad Sveriges Radio: Avgörande datumet – då måste du senast skicka julklapparna.
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2024.11.27 14:40 tehzriz I beat every club. 766 Gold. What meta car should I build now?
 | I beat every club in the game and I wanna buy some crazy engine swapped meta cars. What should I buy and build? Even though I beat every club I don’t know anything about meta cars. Help your boy out! submitted by tehzriz to CarXStreets [link] [comments] |
2024.11.27 14:40 Conscious-Focus2027 I love this new update
 | I have played this game off and on over the years, but now I can’t even get my executrix to 7 stars through the event. Oddly enough, I can still buy the remaining shards through the shop, but I don’t want to do that. I might be done if this persists any longer. submitted by Conscious-Focus2027 to SWGalaxyOfHeroes [link] [comments] |
2024.11.27 14:40 _imherejustforfun A few doubts
I had never read Tolkien's books, but after I started watching TROP I decided to start reading (my books should arrive by Christmas 😃).
After this short introduction I have some doubts that were created by things in the series but that I think maybe the readers can have the answer to.
1st When Sauron says he wants to heal Middle-earth, what would that “healing” be?
- if his plan is to heal, how would this actually happen in practice? what is the lasting peace that he says so much about?
Maybe these are silly questions, but since I don't have the background of the books and the series hasn't set out to explain them better, I'm left with these doubts that perhaps you can clarify.
Thx
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2024.11.27 14:40 MaderPorker What are the recommended Online Flower shops in Cavite area?
Looking for flower shops in cavite that does deliveries.
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2024.11.27 14:40 Grimnir8 Horned
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2024.11.27 14:40 Interesting_Rule3590 test
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2024.11.27 14:40 jvc72 Buy Signal PAXGUSD - 27 Nov 2024 @ 09:37 -> USD2 653.00
Ticker: PAXGUSD
Exchange: CRYPTO
Time: 27 Nov 2024 @ 09:37
Price: USD2 653.00
Link: https://getagraph.com/crypto-currencies/PAXGUSD/ENG
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2024.11.27 14:40 makinsteaknbacon How do I get rid of this?
 | Sorry if this has been posted before. This is just one of the work cars submitted by makinsteaknbacon to subaru [link] [comments] |
2024.11.27 14:40 bubblyybrooke Feeling cozy on a Wednesday morning
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2024.11.27 14:40 Defiant_Cicada_1729 Clogs
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2024.11.27 14:40 AlphaSquared_io Eager to join our closed Beta? Check out our Telelgram!
 | submitted by AlphaSquared_io to AlphaSquared [link] [comments] |
2024.11.27 14:40 pissedwaitress Cashing checks: do I need to go to the exact bank that my account is with, or can I go to any bank that’s the same company?
For example, I got my account at the XYZ bank in Baltimore. If I went to a different XYZ bank, in Towson, would they still be able to cash the check since it’s an XYZ bank location?
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2024.11.27 14:40 Iloveporkpie1986 Word Bearer - Possessed
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2024.11.27 14:40 Stalcraft-player Can we all talk about how op godly is?
In PvP this shit is super op and basically makes your dmg on bosses lvl! This shit must be nerfed or better deleted from game
submitted by Stalcraft-player to AUniversalTime [link] [comments]
2024.11.27 14:40 Kory2405 installing applications like on android.
I bought an iphone 16 pro and it is on ios 18.1.1 , i know jailbreak take years these days, is there a chance to have something like troll store on that version? i really like this phone but i would love the freedom to install apps like on android.
submitted by Kory2405 to jailbreak [link] [comments]
2024.11.27 14:40 questison Greater Albany teachers on strike may lose health insurance coverage
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2024.11.27 14:40 life_is_pure_shit Am I the next Leonardo da Vinci !!!!!!
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2024.11.27 14:40 somerandomredddit Does it happens to you also?
Does it happens to you that your mother or father (doesn’t matter which one) that they don’t care about you at all? They pretend that they love you infront of their friends and guests to show that ”ohh i love my son so much” but in reality they left you alone really helpless? And their friends and family thinks like ”ohh they love you don’t think to much” when they all haven’t seen the reality, how your parents threat you? Do you also struggle with these kind if family problems where they all just left you?
submitted by somerandomredddit to Vent [link] [comments]
2024.11.27 14:40 sammmwichhh State Drug Screening?
Location: KY Job: Health Environmentalist (The Kentucky Department for Public Health)
I just interviewed for this position and they called the next morning with an offer. I’m set to come in for paperwork in a few weeks. I have been smoking the devils lettuce for 15 years even though it’s still illegal where I live. There’s absolutely no way I will test clean even If i quit now, as it would take a few months to be out of my system.
Does this state agency drug test? The job listing said “may require drug screening and background check”. We discussed my background check when I was offered the position. Nothing has been mentioned about a drug screening when I come in.
Additional info: I will have a state vehicle and be under supervision for awhile to complete training and pass exams.
submitted by sammmwichhh to drugtesthelp [link] [comments]
2024.11.27 14:40 4996 [FS] [USA]Rick Owens Memphis Jeans, AWGE x NEEDLES Track Pants
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AWGE x NEEDLES Pants - $40 shipped
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